Regulatory Networks, Legal Federalism, and Multi-Level Regulatory Systems

Systems Level Modeling of Gene Regulatory Networks

Toward a systems-level understanding of developmental regulatory networks.

Developmental regulatory networks constitute all the interconnections among molecular components that guide embryonic development. Developmental transcriptional regulatory networks (TRNs) are circuits of transcription factors and cis-acting DNA elements that control expression of downstream regulatory and effector genes. Developmental networks comprise functional subnetworks that are deployed s...

H∞ Sampled-Data Controller Design for Stochastic Genetic Regulatory Networks

Artificially regulating gene expression is an important step in developing new treatment for system-level disease such as cancer. In this paper, we propose a method to regulate gene expression based on sampled-data measurements of gene products concentrations. Inherent noisy behaviour of Gene regulatory networks are modeled with stochastic nonlinear differential equation. To synthesize feed...

Modeling Basel Regulatory in DSGE with Emphasis on Adequacy Regulatory

In this paper Basel regulation is modeled in Dynamic Stochastic General Equilibrium (DSGE) framework. For this purpose, using data from 1981-2017 for Iran, capital adequacy as an importance regulation is modeled. Results show Basel regulation has procyclical effect. According to the results of the model and according to the realities of economy and banking system of Iran, in recession, lending ...

Towards Legal Knowledge Management Systems for Regulatory Compliance

Maintaining regulatory compliance is an increasing concern. Legal Knowledge Management systems could support the work of compliance managers. However, there are challenges to overcome, of interpreting legal knowledge and mapping it onto business processes. In this discussion paper we determine requirements for Legal Knowledge Management systems that can handle these challenges. We argue that an...